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Product Description With our patented One-Step Skin Care Solution, the 37 Actives High Performance Anti-Aging and Firming Serum provides over 37 anti-aging ingredients in one bottle. Featuring several new important actives â such as Hyaluronic Acid and mushroom extracts â to firm skin, reduce the appearance of wrinkle and lines and improve skin health. These powerful ingredients also help to reverse the free radical attack caused by sugar and environmental pollutants. Brand Story 37 Actives was created by US dermatologist Dr. Macrene Alexiades. 37 Actives products uses anti-aging actives in creams and treatments designed for every skin type, age, and issue.